• Featured Product
  • KD/KO Validated

RSPO2 Polyclonal antibody

RSPO2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (1)





Cat no : 17781-1-AP


CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2

Recommended dilution

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17781-1-AP targets RSPO2 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen RSPO2 fusion protein Ag11216
Full Name R-spondin 2 homolog (Xenopus laevis)
Calculated Molecular Weight 243 aa, 28 kDa
Observed Molecular Weight 33 kDa
GenBank Accession NumberBC027938
Gene Symbol RSPO2
Gene ID (NCBI) 340419
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.



Cardiovasc Res

Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis.

Authors - Bhupesh Singla

Int J Mol Sci

R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice.

Authors - Ahmed A Raslan

J Cancer

miR-497-5p-RSPO2 axis inhibits cell growth and metastasis in glioblastoma.

Authors - Kun Chen

DNA Cell Biol

Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer.

Authors - Lei Gao

Mol Biol Rep

RSPO fusion transcripts in colorectal cancer in Japanese population.

Authors - Kazuya Shinmura

BMC Res Notes

R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.

Authors - S R Jackson
  • KO Validated


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Marc (Verified Customer) (02-14-2023)

Used this antibody for immunofluorescence, but since the expression of this protein in spinal cord is low we used it together with a tyramide amplification kit. In this way, it works very good.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: Spinal Cord