Biotin-conjugated RSPO2 Polyclonal antibody
RSPO2 Polyclonal Antibody for
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
Conjugate
Biotin
Cat no : Biotin-17781
Synonyms
Validation Data Gallery
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
Biotin-17781 targets RSPO2 in applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RSPO2 fusion protein Ag11216 |
| Full Name | R-spondin 2 homolog (Xenopus laevis) |
| Calculated Molecular Weight | 243 aa, 28 kDa |
| Observed Molecular Weight | 33 kDa |
| GenBank Accession Number | BC027938 |
| Gene Symbol | RSPO2 |
| Gene ID (NCBI) | 340419 |
| RRID | AB_2883059 |
| Conjugate | Biotin |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.
