Product Information
25968-1-PBS targets Repetin in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag23257 Product name: Recombinant human RPTN protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 690-784 aa of BC112216 Sequence: QAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR Predict reactive species |
| Full Name | repetin |
| Observed Molecular Weight | 90 kDa |
| GenBank Accession Number | BC112216 |
| Gene Symbol | RPTN |
| Gene ID (NCBI) | 126638 |
| RRID | AB_3742163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6XPR3 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Repetin (also known as RPTN), is a member of the "fused" gene family and localized in the epidermal differentiation complex on chromosome 1q21. Repetin contains 2 N-terminal EF hand motifs, a central domain containing 28 repeats of the consensus sequence QxDRQGQSSHYG, and a glutamine- and arginine-rich C-terminal domain(PMID: 15854042). Repetin is an extracellular epidermal matrix protein involved in forming keratinocyte envelope. Repetin is expressed in the epidermis and at high levels in eccrine sweat glands, the inner sheaths of hair roots, and the filiform papilli of the tongue(PMID: 20448178).
