S100A7/Psoriasin Polyclonal antibody

S100A7/Psoriasin Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC,ELISA

Conjugate

Unconjugated

Cat no : 13061-1-AP

Synonyms

Protein S100 A7, PSOR1, Psoriasin, S100A7, S100A7c



Tested Applications

Positive WB detected inMCF-7 cells
Positive IHC detected inhuman oesophagus cancer tissue, human breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 3 publications below

Product Information

13061-1-AP targets S100A7/Psoriasin in WB, IHC,ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen S100A7/Psoriasin fusion protein Ag3738
Full Name S100 calcium binding protein A7
Calculated molecular weight 101 aa, 11 kDa
Observed molecular weight 11 kDa
GenBank accession numberBC034687
Gene symbol S100A7
Gene ID (NCBI) 6278
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

S100A7 (psoriasin), a member of the S100 protein family, is a well-known antimicrobial peptide and a signaling molecule which regulates cellular function and is expressed in many squamous cell carcinomas (SCCs), such as SCC of the skin. It is an EF-hand type calcium binding protein localized in epithelial cells, regulates cell proliferation and differentiation. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

Protocols

Product Specific Protocols
WB protocol for S100A7/Psoriasin antibody 13061-1-APDownload protocol
IHC protocol for S100A7/Psoriasin antibody 13061-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Mol Med Rep

TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes.

Authors - Xinxin Liu
humanWB

Oncol Lett

PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV-negative head and neck squamous cell carcinoma.

Authors - Yushen Su
humanWB

Cell Biol Int

S100A7 promotes the development of human endometriosis by activating NF-κB signaling pathway in endometrial stromal cells.

Authors - Qingqing Sun