Validation Data Gallery
|Positive WB detected in||MCF-7 cells|
|Positive IHC detected in||human oesophagus cancer tissue, human breast cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||MCF-7 cells|
|Western Blot (WB)||WB : 1:200-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Immunofluorescence (IF)||IF : 1:200-1:800|
|Sample-dependent, check data in validation data gallery|
13061-1-AP targets S100A7/Psoriasin in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
|Host / Isotype||Rabbit / IgG|
|Immunogen||S100A7/Psoriasin fusion protein Ag3738|
|Full Name||S100 calcium binding protein A7|
|Calculated molecular weight||101 aa, 11 kDa|
|Observed molecular weight||11 kDa|
|GenBank accession number||BC034687|
|Gene ID (NCBI)||6278|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
S100A7 (psoriasin), a member of the S100 protein family, is a well-known antimicrobial peptide and a signaling molecule which regulates cellular function and is expressed in many squamous cell carcinomas (SCCs), such as SCC of the skin. It is an EF-hand type calcium binding protein localized in epithelial cells, regulates cell proliferation and differentiation. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
|Product Specific Protocols|
|WB protocol for S100A7/Psoriasin antibody 13061-1-AP||Download protocol|
|IHC protocol for S100A7/Psoriasin antibody 13061-1-AP||Download protocol|
|IF protocol for S100A7/Psoriasin antibody 13061-1-AP||Download protocol|
|Click here to view our Standard Protocols|
J Eur Acad Dermatol Venereol
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
A novel metabolic subtype with S100A7 high expression represents poor prognosis and immuno-suppressive tumor microenvironment in bladder cancer
Cell Biol Int
S100A7 promotes the development of human endometriosis by activating NF-κB signaling pathway in endometrial stromal cells.
PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV-negative head and neck squamous cell carcinoma.
Mol Med Rep
TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes.
J Periodontal Res
Effects of prolonged stimulation with heated tobacco products (Ploom TECH+ ) on gingival epithelial cells