SCN7A-Specific Recombinant monoclonal antibody

• 

  WB analysis of HeLa using 85797-1-RR

  HeLa cells were subjected to SDS PAGE followed by western blot with 85797-1-RR (SCN7A-Specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse heart using 85797-1-RR

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 85797-1-RR (SCN7A-Specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

SCN7A-Specific Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 85797-1-RR

Clone No.250004D8

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

SCN7A, Atypical sodium channel Nav2.1, Sodium channel protein type 7 subunit alpha

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Tested Applications

• Positive WB detected in: HeLa cells, mouse heart tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

85797-1-RR targets SCN7A-Specific in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: sodium channel, voltage-gated, type VII, alpha
• Calculated Molecular Weight: 193 kDa
• Observed Molecular Weight: 180 kDa
• GenBank Accession Number: NM_002976
• Gene Symbol: SCN7A
• Gene ID (NCBI): 6332
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q01118
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SCN7A, also named as SCN6A, belongs to the sodium channel family. SCN7A mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, SCN7A forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This antibody is specific to SCN7A.