|Positive WB detected in
|human peripheral blood platelets, Jurkat cells
|Positive IP detected in
|Western Blot (WB)
|WB : 1:2000-1:10000
|IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
60322-1-Ig targets P-selectin / CD62P in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human samples.
|human, mouse, rat
|Host / Isotype
|Mouse / IgG2b
|P-selectin / CD62P fusion protein Ag4124
|selectin P (granule membrane protein 140kDa, antigen CD62)
|Calculated molecular weight
|830 aa, 91 kDa
|Observed molecular weight
|140 kDa, 105-110 kDa
|GenBank accession number
|Gene ID (NCBI)
|Protein A purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
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