SEMA4B Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• SEMA4B Polyclonal antibody, PBS Only (29191-1-PBS)

• 

  IHC staining of human colon cancer using 29191-1-AP (same clone as 29191-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 29191-1-AP (SEMA4B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29191-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 29191-1-AP (same clone as 29191-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 29191-1-AP (SEMA4B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29191-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 29191-1-AP (same clone as 29191-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 29191-1-AP (SEMA4B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29191-1-PBS in a different storage buffer formulation.

SEMA4B Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 29191-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

KIAA1745, SEMAC, SemC

---

Product Information

29191-1-PBS targets SEMA4B in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag30422

  Product name: Recombinant human SEMA4B protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 92-256 aa of BC110853

  Sequence: ALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGSLQGD

• Full Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
• GenBank Accession Number: BC110853
• Gene Symbol: SEMA4B
• Gene ID (NCBI): 10509
• RRID: AB_3086102
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NPR2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SEMA4B (Semaphorin 4B), belonging to the Class SEMA4, is a transmembrane homodimer glycoprotein. Lots of SEMA4 family members have been implicated in the formation and progression of tumors due to (PMID: 35676688). SEMA4B inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation (PMID: 25746385).