Serpin A12/Vaspin Recombinant antibody

• 

  WB analysis of human adipose using 85908-5-RR

  Human adipose tissue was subjected to SDS PAGE followed by western blot with 85908-5-RR (SERPINA12/Vaspin antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

Serpin A12/Vaspin Uni-rAb^TM Recombinant Antibody for WB, ELISA

Cat No. 85908-5-RR

Clone No.250315H1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

SERPINA12, Vaspin, OL 64, OL-64, Serpin A12

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Tested Applications

• Positive WB detected in: human adipose tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

85908-5-RR targets Serpin A12/Vaspin in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Serpin A12/Vaspin fusion protein Eg2842
• Full Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
• Calculated Molecular Weight: 47 kDa
• Observed Molecular Weight: 47-50 kDa
• GenBank Accession Number: NM_001304461.1
• Gene Symbol: Vaspin
• Gene ID (NCBI): 145264
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8IW75
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SERPINA12 is also named as Serpin A12 and Visceral adipose tissue-derived serine protease inhibitor (Vaspin). Vaspin is an adipokine belonging to the serpin family, thus also named SERPINA12, with targets in kallikrein 7 and 14 that participates in skin desquamation (PMID: 34359881). Vaspin is a compensatory molecule in obesity and insulin resistance (PMID: 18321232). Vaspin is a newly described adipokine with an insulin sensitizing effect and inhibitory impact on food intake (PMID: 16030142, PMID: 21465327).