Product Information
86170-1-PBS targets SF3A1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | SF3A1 fusion protein Ag8196 Predict reactive species |
Full Name | splicing factor 3a, subunit 1, 120kDa |
Calculated Molecular Weight | 793 aa, 89 kDa |
Observed Molecular Weight | 120 kDa |
GenBank Accession Number | BC007684 |
Gene Symbol | SF3A1 |
Gene ID (NCBI) | 10291 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q15459 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
SF3A1, also known as SF3a120, is a 793 amino acid protein, which is a Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. SF3A1 also be involved in the assembly of the 'E' complex. The calculated molecular weight of SF3A1 is 88 kDa, but the modified SF3A1 is about 115-120 kDa.(PMID: 7489498 )