SFRS2IP Polyclonal antibody

• 

  WB analysis using 28098-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 28098-1-AP (SFRS2IP antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• Featured Product
• KD/KO Validated

SFRS2IP Polyclonal Antibody for WB, ELISA

Cat No. 28098-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

CASP11, CTD-associated SR protein 11, NY-REN-40, Protein SCAF11, Renal carcinoma antigen NY-REN-40

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Tested Applications

• Positive WB detected in: HEK-293T cells, HeLa cells, Jurkat cells, MCF-7 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 1 publications below

Product Information

28098-1-AP targets SFRS2IP in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag24381

  Product name: Recombinant human SFRS2IP protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 183-523 aa of BC033589

  Sequence: GYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQS

• Full Name: splicing factor, arginine/serine-rich 2, interacting protein
• Calculated Molecular Weight: 1463 aa, 165 kDa
• Observed Molecular Weight: 240 kDa
• GenBank Accession Number: BC033589
• Gene Symbol: SFRS2IP
• Gene ID (NCBI): 9169
• RRID: AB_2881059
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q99590
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SFRS2IP, also known as CASP11, SCAF11 SIP1, SRSF2IP, is a 1463 amino acid protein, which Interacts with SRSF2/SFRS2, U2AF2 and SNRNP70. SFRS2IP plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly (PMID: 9447963).

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Front Med (Lausanne); A Prognostic Signature Consisting of Pyroptosis-Related Genes and SCAF11 for Predicting Immune Response in Breast Cancer.; Authors - Ling Chu ; KD Validated