SHANK1 Recombinant monoclonal antibody, PBS Only

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• SHANK1 Recombinant monoclonal antibody, PBS Only (86842-1-PBS)

• 

  WB analysis using 86842-1-RR (same clone as 86842-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86842-1-RR (SHANK1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86842-1-PBS in a different storage buffer formulation.

SHANK1 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86842-1-PBS

Clone No.251628B1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

SHANK 1, Shank1a, Somatostatin receptor-interacting protein, SPANK 1, SPANK1

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Product Information

86842-1-PBS targets SHANK1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: SH3 and multiple ankyrin repeat domains 1
• Calculated Molecular Weight: 225 kDa
• Observed Molecular Weight: 159-225 kDa
• GenBank Accession Number: NM_016148
• Gene Symbol: SHANK1
• Gene ID (NCBI): 50944
• RRID: AB_3745156
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9Y566
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SHANK1 belongs to the SHANK family. It seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK1 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. The antibody is specific to SHANK1.