SLC1A5/ASCT2 Recombinant monoclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• Recombinant Antibodies
• SLC1A5/ASCT2 Recombinant monoclonal antibody, PBS Only (87833-2-PBS)

• 

  WB analysis using 87833-2-RR (same clone as 87833-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 87833-2-RR (RDRC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87833-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 87833-2-RR (same clone as 87833-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 87833-2-RR (SLC1A5/ASCT2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87833-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 87833-2-RR (same clone as 87833-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 87833-2-RR (SLC1A5/ASCT2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87833-2-PBS in a different storage buffer formulation.

SLC1A5/ASCT2 Uni-rAb^® Recombinant Antibody for WB, IHC, Indirect ELISA

Cat No. 87833-2-PBS

Clone No.253442A8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

SLC1A5, AAAT, ASCT2, ATB(0), ATBO

---

Product Information

87833-2-PBS targets SLC1A5/ASCT2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: solute carrier family 1 (neutral amino acid transporter), member 5
• Calculated Molecular Weight: 541 aa, 57 kDa
• Observed Molecular Weight: 55-70 kDa
• GenBank Accession Number: BC000062
• Gene Symbol: SLC1A5/ASCT2
• Gene ID (NCBI): 6510
• RRID: AB_3745776
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q15758
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SLC1A5 (Solute Carrier Family 1, member 5), also named as ASCT2, a major glutamine transporter belonging to the SLC1 family and localized in the plasma membrane of several body districts. Consistent with the functions exerted by glutamine, SLC1A5 is involved in uptake of essential amino acids, activation of mTORC1 and glutamine-dependent tumor cell survival and growth. SLC1A5 is highly expressed in various malignancies and plays a critical role in the transformation, growth and survival of cancer cells (PMID: 30234109). High SLC1A5 expression is associated with poor prognosis in clear-cell renal cell carcinoma (PMID: 26599282).