ZnT7 Polyclonal antibody

ZnT7 Polyclonal Antibody for IF, IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 13966-1-AP

Synonyms

SLC30A7, Zinc transporter 7, ZnT 7, Znt like transporter 2, ZNT7, ZnTL2



Tested Applications

Positive WB detected inC2C12 cells, HEK-293 cells, NCI-H1299 cells
Positive IHC detected inhuman lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inA431 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

13966-1-AP targets ZnT7 in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ZnT7 fusion protein Ag4957
Full Name solute carrier family 30 (zinc transporter), member 7
Calculated molecular weight 42 kDa
Observed molecular weight 42 kDa
GenBank accession numberBC064692
Gene symbol SLC30A7
Gene ID (NCBI) 148867
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for ZnT7 antibody 13966-1-APDownload protocol
IHC protocol for ZnT7 antibody 13966-1-APDownload protocol
IF protocol for ZnT7 antibody 13966-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Acta Neuropathol Commun

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.

Authors - Alexandra Grubman
mouseWB

Metallomics

Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?

Authors - Alexandra Grubman
humanWB

FEBS Open Bio

ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function.

Authors - Surapun Tepaamorndech
mouseWB,IHC

Biol Open

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.

Authors - Kanninen Katja M KM
human, mouseWB, IF

J Neurosci Res

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Authors - Masayuki Kaneko
mouseWB

Am J Physiol Gastrointest Liver Physiol

Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease.

Authors - Qian Sun