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  • KD/KO Validated

SLC30A8/ZNT8-Specific Polyclonal antibody

SLC30A8/ZNT8-Specific Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (1)





Cat no : 16169-1-AP


SLC30A8, SLC30A8/ZNT8-Specific, Zinc transporter 8, ZnT 8, ZNT8

Tested Applications

Positive WB detected inmouse pancreas tissue
Positive IHC detected inhuman pancreas tissue, human pancreas cancer tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inhuman pancreas tissue

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

16169-1-AP targets SLC30A8/ZNT8-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse, rat, Yellow catfish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name solute carrier family 30 (zinc transporter), member 8
Calculated molecular weight 41 kDa
Observed molecular weight 45-50 kDa
GenBank accession numberNM_173851
Gene symbol SLC30A8
Gene ID (NCBI) 169026
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SLC30A8 (also named as ZNT8) encods the secretory granule zinc transporter, permiting cellular efflux of zinc. SLC30A8 was recently defined as a autoantigen candidates of type 2 diabetes, although the molecular mechanism through which this phenotype is manifest is incompletely understood.


Product Specific Protocols
WB protocol for SLC30A8/ZNT8-Specific antibody 16169-1-APDownload protocol
IHC protocol for SLC30A8/ZNT8-Specific antibody 16169-1-APDownload protocol
IF protocol for SLC30A8/ZNT8-Specific antibody 16169-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Invest Ophthalmol Vis Sci

Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.

Authors - Guoxu Xu
  • KD Validated
Yellow catfishWB

Biochim Biophys Acta Gene Regul Mech

Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.

Authors - Chang-Chun Song

Sci Rep

Syngeneically transplanted insulin producing cells differentiated from adipose derived stem cells undergo delayed damage by autoimmune responses in NOD mice.

Authors - Kazunori Tokuda

Sci Rep

A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.

Authors - Shogo Ohta

J Endocrinol

Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine induced cell death.

Authors - Maria Karsai

J Biol Chem

A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.

Authors - Chengfeng Merriman