SLC4A8 Polyclonal antibody

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• SLC4A8 Polyclonal antibody (12531-1-AP)

SLC4A8 Polyclonal Antibody for WB, ELISA

Cat No. 12531-1-AP Copied!

Publications (3)

Download datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

Electroneutral Na(+)-driven Cl-HCO3 exchanger, k NBC3, KIAA0739, k-NBC3, NBC

• 

  WB analysis of human brain using 12531-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 12531-1-AP (SLC4A8 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of mouse brain using 12531-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 12531-1-AP (SLC4A8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: human brain tissue, mouse brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

12531-1-AP targets SLC4A8 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag3227

  Product name: Recombinant human SLC4A8 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-352 aa of BC025994

  Sequence: MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQ

• Full Name: solute carrier family 4, sodium bicarbonate cotransporter, member 8
• Calculated Molecular Weight: 691 aa, 77 kDa
• Observed Molecular Weight: 121 kDa
• GenBank Accession Number: BC025994
• Gene Symbol: SLC4A8
• Gene ID (NCBI): 9498
• RRID: AB_10640898
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q2Y0W8
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

What published studies show

The SLC4A8 Polyclonal antibody (Cat# 12531-1-AP) has 3 total citations. These appear in Cell Metabolism, Molecular Cell, and American Journal of Physiology – Renal Physiology. The associated research fields include renal physiology and electrolyte transport (mineralocorticoid receptor signaling, potassium stress, sodium transport), and cell metabolism (mTORC1-mediated bicarbonate import and de novo nucleotide synthesis). All citations used the antibody for Western blot in human or mouse samples.

Automatically generated from the 3 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
mouse	WB	Cell Metab; Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.; Authors - Shibata Shigeru S
human	WB	Mol Cell; The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.; Authors - Eunus S Ali
mouse	WB	Am J Physiol Renal Physiol; Effects of extreme potassium stress on blood pressure and renal tubular sodium transport.; Authors - Cary R Boyd-Shiwarski