SLITRK2 Polyclonal antibody

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• SLITRK2 Polyclonal antibody (21508-1-AP)

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  IHC staining of mouse brain using 21508-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21508-1-AP (SLITRK2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of mouse brain using 21508-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21508-1-AP (SLITRK2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SLITRK2 Polyclonal Antibody for IHC, ELISA

Cat No. 21508-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Synonyms

CXorf2, KIAA1854, SLIT and NTRK like protein 2, SLITL1, SLITRK 2

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Tested Applications

• Positive IHC detected in: mouse brain tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

21508-1-AP targets SLITRK2 in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag15993

  Product name: Recombinant human SLITRK2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 643-830 aa of BC113012

  Sequence: VLKRRKGVPSVPRNTNNLDVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEP

• Full Name: SLIT and NTRK-like family, member 2
• Calculated Molecular Weight: 845 aa, 95 kDa
• GenBank Accession Number: BC113012
• Gene Symbol: SLITRK2
• Gene ID (NCBI): 84631
• RRID: AB_3742039
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H156
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SLITRK2 is a 845 amino acid single-pass transmembrane protein and is expressed at postsynaptic neurons, which plays a important role in regulating neurite outgrowth and excitatory synapse maintenance (PMID: 35840571). It has been reported that SLITRK2 deficiency could lead to abnormal neural network activity, vestibular function, synaptic integrity, and serotonergic function (PMID: 35789858).