SLX4IP Polyclonal antibody, PBS Only

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• SLX4IP Polyclonal antibody, PBS Only (30497-1-PBS)

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  WB analysis using 30497-1-AP (same clone as 30497-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30497-1-AP (SLX4IP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30497-1-PBS in a different storage buffer formulation.

SLX4IP Polyclonal Antibody for WB, Indirect ELISA

Cat No. 30497-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

C20orf94, bA204H22.1, bA254M13.1, UPF0492 protein C20orf94

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Product Information

30497-1-PBS targets SLX4IP in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag33034

  Product name: Recombinant human SLX4IP protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 160-408 aa of

  Sequence: KLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH

• Full Name: chromosome 20 open reading frame 94
• Calculated Molecular Weight: 46 kDa
• Observed Molecular Weight: 42 kDa
• Gene Symbol: C20orf94
• Gene ID (NCBI): 128710
• RRID: AB_3742346
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q5VYV7
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SLX4IP is a nuclear adaptor protein that associates with the SLX4 DNA repair scaffold, contributing to DNA damage repair, replication stress responses, and telomere maintenance. By regulating nuclease-containing repair complexes and potentially supporting ALT-mediated telomere elongation, SLX4IP plays an important role in maintaining genomic stability. Dysregulation of SLX4IP has been implicated in cancer biology, particularly in tumors utilizing alternative telomere maintenance pathways.