SOX1 Polyclonal antibody

SOX1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Publications

2

Cat no : 20744-1-AP

Synonyms

SOX1, Transcription factor SOX 1

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Validation Data Gallery

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  WB analysis of NCCIT using 20744-1-AP

  NCCIT cell were subjected to SDS PAGE followed by western blot with 20744-1-AP (SOX1 Antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: NCCIT cell

Recommended dilution

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IF: See 1 publications below

Product Information

20744-1-AP targets SOX1 in WB, IF, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: SRY (sex determining region Y)-box 1
• Calculated Molecular Weight: 39 kDa
• Observed Molecular Weight: 45-50 kDa
• GenBank Accession Number: NM_005986
• Gene Symbol: SOX1
• Gene ID (NCBI): 6656
• RRID: AB_2878732
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX1 may function as a switch in neuronal development and Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

Publications

Species	Application	Title
human	IF	Mater Today Bio; Nanofiber-microwell cell culture system for spatially patterned differentiation of pluripotent stem cells in 3D; Authors - Youyi Tai
human	WB	J Cell Mol Med; Down-regulation of exosomal miR-200c derived from keratinocytes in vitiligo lesions suppresses melanogenesis.; Authors - Chaoshuai Zhao