SOX12 Polyclonal antibody

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SOX12 Polyclonal Antibody for WB, ELISA

Cat No. 23939-1-AP Copied!

Publications (12)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IP, ChIP, RIP, ELISA

Synonyms

Protein SOX 22, Protein SOX-22, SOX22, Transcription factor SOX 12, Transcription factor SOX-12

• 

  WB analysis of mouse testis using 23939-1-AP

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 23939-1-AP (SOX12 Antibody) at dilution of 1:1000 incubated at 4 degree celsius over night.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of BxPC-3 using 23939-1-AP

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 23939-1-AP (SOX12 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of mouse brain using 23939-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 23939-1-AP (SOX12 Antibody) at dilution of 1:600 incubated at 4 degree celsius over night.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of mouse testis using 23939-1-AP

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 23939-1-AP (SOX12 Antibody) at dilution of 1:300 incubated at 4 degree celsius over night.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: mouse testis tissue, mouse brain tissue, BxPC-3 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

23939-1-AP targets SOX12 in WB, IP, ChIP, RIP, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag21043

  Product name: Recombinant human SOX12 protein

  Source: e coli.-derived, PET30a

  Tag: 6*His

  Domain: 1-315 aa of BC067361

  Sequence: MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGPAGLDCSALDRDPDLQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY

• Full Name: SRY (sex determining region Y)-box 12
• Calculated Molecular Weight: 315 aa, 34 kDa
• Observed Molecular Weight: 35-40 kDa
• GenBank Accession Number: BC067361
• Gene Symbol: SOX12
• Gene ID (NCBI): 6666
• RRID: AB_2879368
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• UNIPROT ID: O15370
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

What published studies show

The SOX12 antibody (Cat# 23939-1-AP) has 12 total citations published in journals including Science, Cell Death & Disease, Molecular Therapy Nucleic Acids, Cancer Gene Therapy, Cancer Biology & Therapy, Experimental Cell Research, Molecular Carcinogenesis, Journal of Cancer Research and Clinical Oncology, Annals of Translational Medicine, Environmental Toxicology, and Biochemistry and Cell Biology. Research fields span protein degradation pathways, thyroid cancer metastasis, hepatocellular carcinoma, breast cancer, lung cancer, multiple myeloma, colorectal cancer, gastric cancer, glioma, and esophageal cancer.

Automatically generated from the 12 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Science; The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation; Authors - Xin Gu
human	ChIP	Cell Death Dis; The SOX12-YBX1-LDHA signaling axis drives metastasis in papillary thyroid carcinoma.; Authors - Xianhui Ruan
mouse	WB	Mol Ther Nucleic Acids; lncRNA PRR34-AS1 promotes HCC development via modulating Wnt/β-catenin pathway by absorbing miR-296-5p and upregulating E2F2 and SOX12.; Authors - Minzhen Qin
human	WB	Cancer Gene Ther; LncRNA UCA1 promotes SOX12 expression in breast cancer by regulating m6A modification of miR-375 by METTL14 through DNA methylation.; Authors - Chengpeng Zhao
human	WB,IP	Cancer Biol Ther; Hypoxia promotes non-small cell lung cancer cell stemness, migration, and invasion via promoting glycolysis by lactylation of SOX9; Authors - Fei Yan
human	WB	Exp Cell Res; LncRNA LINC00680 promotes lung adenocarcinoma growth via binding to GATA6 and canceling GATA6-mediated suppression of SOX12 expression.; Authors - Xiaojuan Sun ; KD Validated