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  • KD/KO Validated

SOX13 Polyclonal antibody

SOX13 Polyclonal Antibody for IF, IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IP, IHC, IF, chIP, ELISA

Conjugate

Unconjugated

Cat no : 18902-1-AP

Synonyms

ICA12, Islet cell antigen 12, Sox 13, SOX13, Transcription factor SOX 13



Tested Applications

Positive WB detected inBGC-823 cells, NCI-H1299 cells
Positive IP detected inSH-SY5Y cells
Positive IF detected inHela cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunofluorescence (IF)IF : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

18902-1-AP targets SOX13 in WB, IP, IHC, IF, chIP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SOX13 fusion protein Ag13537
Full Name SRY (sex determining region Y)-box 13
Calculated molecular weight 622 aa, 69 kDa
Observed molecular weight 69 kDa
GenBank accession numberBC106038
Gene symbol SOX13
Gene ID (NCBI) 9580
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SRY-BOX 13(SOX13), identified a sequence homologous more than 60% to the SRY HMG box ,with a centrally located HMG box and an N-terminal leucine zipper motif with a neighboring glutamine stretch called a Q box. SOX13 binds to the consensus HMG-box motif. It's an IDDM-specific human autoantigen, and a gamma-delta-specific gene in the immune system. It can modulates Wnt/TCF activity. This is a rabbit polyclonal raised against part of N-terminal chain of SOX13 of human origin.

Protocols

Product Specific Protocols
WB protocol for SOX13 antibody 18902-1-APDownload protocol
IF protocol for SOX13 antibody 18902-1-APDownload protocol
IP protocol for SOX13 antibody 18902-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IF

Front Cardiovasc Med

Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells

Authors - Catherine Demos
  • KD Validated
humanWB,IHC

Lab Invest

Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.

Authors - Min Feng
  • KD Validated
mouseWB, IF

Mol Cell Biochem

Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.

Authors - Mikella Daigle
humanWB,IHC

Bioengineered

Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.

Authors - Xiaoyan Jin
  • KD Validated
humanWB,chIP

J Exp Clin Cancer Res

FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma.

Authors - Zhenwei He