• Featured Product
  • KD/KO Validated

FDFT1 Polyclonal antibody

FDFT1 Polyclonal Antibody for IF, IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IP, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 13128-1-AP

Synonyms

DGPT, ERG9, FDFT1, FPP:FPP farnesyltransferase, SQS, Squalene synthase, SS



Tested Applications

Positive WB detected inHepG2 cells
Positive IP detected inCOLO 320 cells
Positive IF detected inL02 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

13128-1-AP targets FDFT1 in WB, IP, IHC, IF,ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FDFT1 fusion protein Ag3743
Full Name farnesyl-diphosphate farnesyltransferase 1
Calculated molecular weight 417 aa, 48 kDa
Observed molecular weight 48 kDa
GenBank accession numberBC029641
Gene symbol FDFT1
Gene ID (NCBI) 2222
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for FDFT1 antibody 13128-1-APDownload protocol
IF protocol for FDFT1 antibody 13128-1-APDownload protocol
IP protocol for FDFT1 antibody 13128-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Nat Commun

A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition.

Authors - Christopher E Mahoney
  • KO Validated
humanWB,IHC

Arch Biochem Biophys

20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.

Authors - Jiaojiao Lu
mouseWB

Neuron

Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.

Authors - Xiaohui Li
mouseWB

Cell Metab

Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer.

Authors - Douglas E Biancur
  • KD Validated
human,mouseWB

Nature

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.

Authors - Xiao-Yi Lu