SRCRB4D Polyclonal antibody

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• SRCRB4D Polyclonal antibody (11350-1-AP)

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  WB analysis using 11350-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 11350-1-AP (SRCRB4D antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

SRCRB4D Polyclonal Antibody for WB, ELISA

Cat No. 11350-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

Four scavenger receptor cysteine-rich domains-containing protein, S4D-SRCRB, Scavenger receptor cysteine-rich domain-containing group B protein, SSC4D

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Tested Applications

• Positive WB detected in: mouse kidney tissue, rat kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

11350-1-AP targets SRCRB4D in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag1884

  Product name: Recombinant human SRCRB4D protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-190 aa of BC015651

  Sequence: MTGTLRTRAWPAAKRAAGLRWALRDEARLSDCFHLGWGQHNCGHHEDAGALCAGEADSEGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS

• Full Name: scavenger receptor cysteine rich domain containing, group B (4 domains)
• Calculated Molecular Weight: 61 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC015651
• Gene Symbol: SRCRB4D
• Gene ID (NCBI): 136853
• RRID: AB_3741817
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8WTU2
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SRCRB4D (also known as SSC4D or S4D-SRCRB) is a soluble, secreted pattern-recognition receptor belonging to the scavenger receptor cysteine-rich (SRCR) superfamily, characterized by four group B SRCR domains. It is broadly expressed in epithelial cells of the kidney, placenta, liver, intestine, and lung, and functions as an innate immune sensor capable of binding diverse bacteria and protozoan parasites, thereby enhancing phagocytosis by monocytes.