ST7 Polyclonal antibody, PBS Only

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• ST7 Polyclonal antibody, PBS Only (11945-1-PBS)

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  WB analysis using 11945-1-AP (same clone as 11945-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11945-1-AP (ST7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11945-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 11945-1-AP (same clone as 11945-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 11945-1-AP (ST7 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11945-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 11945-1-AP (same clone as 11945-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11945-1-AP (ST7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11945-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 11945-1-AP (same clone as 11945-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11945-1-AP (ST7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11945-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 11945-1-AP (same clone as 11945-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 11945-1-AP (ST7 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11945-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 11945-1-AP (same clone as 11945-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 11945-1-AP (ST7 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11945-1-PBS in a different storage buffer formulation.

ST7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 11945-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

11945-1-PBS targets ST7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag2547

  Product name: Recombinant human ST7 protein

  Source: e coli.-derived, T-GST

  Tag: GST

  Domain: 101-481 aa of BC030954

  Sequence: LRPLLGGVDNNSSNNSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINECATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKE

• Full Name: suppression of tumorigenicity 7
• Calculated Molecular Weight: 63 kDa
• Observed Molecular Weight: 63 kDa
• GenBank Accession Number: BC030954
• Gene Symbol: ST7
• Gene ID (NCBI): 7982
• RRID: AB_2270936
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NRC1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Human ST7 (suppressor of tumorigenicity 7) gene, also called FAM4A1, HELG or RAY1, maps to a region on chromosome 7 identified as an autism-susceptibility locus. ST7 has been proposed to be a tumor suppressor gene with highest expression in heart, liver and pancreas. The product of this gene is a multi-pass membrane protein belonging to the ST7 family, full-length ST7 cDNA has been cloned and verified in cancer cell lines, recent result suggests that ST7 may mediate tumor suppression through the regulation of the genes involved in maintaining the cellular structure of the cell and involved in oncogenic pathways.