STK24 Polyclonal antibody

STK24 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

2

Cat no : 13579-1-AP

Synonyms

MST 3, MST3, MST3B, STE20, STE20 like kinase MST3, STK24, STK3

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Validation Data Gallery

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  WB analysis of HeLa using 13579-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 13579-1-AP (STK24 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 1 publications below

Product Information

13579-1-AP targets STK24 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: STK24 fusion protein Ag4483
• Full Name: serine/threonine kinase 24 (STE20 homolog, yeast)
• Calculated Molecular Weight: 431 aa, 48 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC035578
• Gene Symbol: STK24
• Gene ID (NCBI): 8428
• RRID: AB_2198769
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Serine/threonine-protein kinase 24 (STK24), also named MST3, belonging to GCK subfamily of STE20-like kinases, acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation (PubMed: 10644707, PMID:12107159). STK24 and STK25 operate in the same cardiovascular development pathway with programmed cell death 10 (CCM3) (PMID: 20332113). It regulates axon outgrowth in forebrain neurons (PubMed: 17114295).

Publications

Species	Application	Title
rat		Biomed Pharmacother; Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.; Authors - Jiexian Du
human	WB	Mediators Inflamm; STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment; Authors - Yadong Li ; KD Validated