SUCLA2 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 12627-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-3 cells, HEK-293 cells, HepG2 cells, L02 cells, mouse brain tissue, mouse liver tissue, SH-SY5Y cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human colon cancer tissue, human heart tissue, human kidney tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
succinate-CoA ligase, ADP-forming, beta subunit

Calculated molecular weight:
463aa,50 kDa

Observed molecular weight:
48-50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SUCLA2

Synonyms
A BETA, SCS betaA, SUCLA2
Background

SUCLA2(succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial) is also named as SCS-betaA and belongs to the succinate/malate CoA ligase beta subunit family. It can catalyzes the ATP-dependent ligation of succinate and CoA to form succinyl-CoA.Defects in SUCLA2 are the cause of mitochondrial DNA depletion syndrome type 5 (MTDPS5).


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