SUV39H2 Polyclonal antibody

• Featured Product
• KD/KO Validated

SUV39H2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, ELISA

Conjugate

Unconjugated

Publications

9

Cat no : 11338-1-AP

Synonyms

H3 K9 HMTase 2, KMT1B, Lysine N methyltransferase 1B, Su(var)3 9 homolog 2, SUV39H2

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Validation Data Gallery

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  WB analysis of HEK-293 using 11338-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 11338-1-AP (SUV39H2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HEK-293 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 8 publications below
• IHC: See 1 publications below
• IP: See 2 publications below

Product Information

11338-1-AP targets SUV39H2 in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SUV39H2 fusion protein Ag1882
• Full Name: suppressor of variegation 3-9 homolog 2 (Drosophila)
• Calculated Molecular Weight: 53 kDa
• Observed Molecular Weight: 53 kDa
• GenBank Accession Number: BC007754
• Gene Symbol: SUV39H2
• Gene ID (NCBI): 79723
• RRID: AB_2196730
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

Species	Application	Title
		Nucleic Acids Res; ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication; Authors - Huanzhou Xu
mouse	WB	Hepatology; The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice.; Authors - Zhiwen Fan ; KO Validated
human	WB,IHC,IP	Cell Death Differ; Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration; Authors - Huaizhen Liang
mouse	WB,IP	Nucleic Acids Res; DICER regulates the expression of major satellite repeat transcripts and meiotic chromosome segregation during spermatogenesis.; Authors - Ram Prakash Yadav
human	WB	Nucleic Acids Res; Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions.; Authors - Oriane Mauger
mouse	WB	Biochem Biophys Res Commun; Suv39h2 deficiency ameliorates diet-induced steatosis in mice.; Authors - Jing Shao