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  • KD/KO Validated

SUV39H2 Polyclonal antibody

SUV39H2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, IP, ELISA

H3 K9 HMTase 2, KMT1B, Lysine N methyltransferase 1B, Su(var)3 9 homolog 2, SUV39H2

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 
SKU: 

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Freight/Packing: -

Quantity

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Tested Applications

Positive WB detected inHEK-293 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11338-1-AP targets SUV39H2 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag1882

Product name: Recombinant human SUV39H2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 44-350 aa of BC007754

Sequence: VKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN

Predict reactive species
Full Name suppressor of variegation 3-9 homolog 2 (Drosophila)
Calculated Molecular Weight 53 kDa
Observed Molecular Weight 53 kDa
GenBank Accession NumberBC007754
Gene Symbol SUV39H2
Gene ID (NCBI) 79723
RRIDAB_2196730
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H5I1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Protocols

Product Specific Protocols
WB protocol for SUV39H2 antibody 11338-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

What published studies show

The Anti-SUV39H2 antibody (Cat# 11338-1-AP) has 17 citations across journals including Cell Metabolism, Nature Communications, Hepatology, Molecular Cell, Nucleic Acids Research, Advanced Science, Cell Death & Differentiation, JBC, Frontiers in Oncology, Epigenomics, Sci Advances, and others. Research fields span epigenetics and heterochromatin biology, histone modification, cancer (breast, glioblastoma, nasopharyngeal), lipid metabolism/NAFLD, stem cell biology, autophagy, and spermatogenesis.

SpeciesApplicationTitle
human, mouseWB,IP

Cell Metab

Pregnenolone promotes immune evasion through blocking endogenous retrovirus expression.

Authors - Changsheng Huang
mouseWB

Nat Commun

Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.

Authors - Ming Xiao
mouseWB

Hepatology

The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice.

Authors - Zhiwen Fan
  • KO Validated
mouseWB

Mol Cell

Requirements for establishment and epigenetic stability of mammalian heterochromatin

Authors - Antonis Tatarakis
  • KD Validated
mouseWB

Nucleic Acids Res

The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression

Authors - Dan Guo
humanWB

Nucleic Acids Res

Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions.

Authors - Oriane Mauger
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