SYN2 Polyclonal antibody

SYN2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

4

Cat no : 16573-1-AP

Synonyms

SYN2, synapsin II, SYNII, SYNIIa, SYNIIb

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Validation Data Gallery

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  WB analysis using 16573-1-AP

  mouse brain tissue was subjected to SDS PAGE followed by western blot with 16573-1-AP (SYN2 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse brain using 16573-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 16573-1-AP (SYN2 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 4 publications below

Product Information

16573-1-AP targets SYN2 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SYN2 fusion protein Ag9855
• Full Name: synapsin II
• Calculated Molecular Weight: 582 aa, 63 kDa
• Observed Molecular Weight: 70 kDa, 55 kDa
• GenBank Accession Number: BC051307
• Gene Symbol: SYN2
• Gene ID (NCBI): 6854
• RRID: AB_2878281
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Synapsins (synapsin I, II, III) are a family of synaptic vesicle phosphoproteins that have been implicated in modulation of neurotransmitter release and in synaptogenesis. Synapsin II (SYN2) is composed of two isoforms, synapsin IIa and IIb.

Publications

Species	Application	Title
mouse	WB	Brain Behav Immun; Hippocampal alpha-synuclein mediates depressive-like behaviors.; Authors - Tingfu Du
mouse	WB	Eur J Pharmacol; Investigation of rhodamine derivative on behavioral impairment in a double neurotoxin lesion of substantia nigra and locus coeruleus dysfunctional mice; Authors - Zhili Ren
human	WB	Genes Dis; The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1; Authors - Min Wang
mouse	WB	Int Immunopharmacol; pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway; Authors - Qinglan Zong