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SYTL2 Polyclonal antibody

SYTL2 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 12359-1-AP


CHR11SYT, Exophilin 4, KIAA1597, SGA72M, SLP2, SLP2A, synaptotagmin like 2, Synaptotagmin like protein 2, SYTL2

Tested Applications

Positive WB detected inA549 cells, Jurkat cells, MCF-7 cells
Positive IHC detected inhuman breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:3000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

12359-1-AP targets SYTL2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SYTL2 fusion protein Ag3023
Full Name synaptotagmin-like 2
Calculated Molecular Weight 934 aa, 105 kDa
Observed Molecular Weight39 kDa, 100-105 kDa
GenBank Accession NumberBC015540
Gene Symbol SYTL2
Gene ID (NCBI) 54843
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Synaptotagmin-like 2 (SYTL2) is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. SYTL2 contains an N-terminal Slp homology domain (SHD), Rab-binding region, and C-terminal tandem C2 domains, C2A and C2B (PMID: 11327731). It interacts with RAB27A and plays a role in promoting docking of RAB27-bound organelles to the plasma membrane (PMID: 17052176). Alternative splicing of SYTL2 gene results in multiple transcript variants encoding distinct isoforms with calculated molecular weights ranging from 39 kDa to 142 kDa.


Product Specific Protocols
WB protocol for SYTL2 antibody 12359-1-APDownload protocol
IHC protocol for SYTL2 antibody 12359-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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