Serpin C1/Antithrombin III Recombinant monoclonal antibody

• 

  WB analysis using 86067-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86067-4-RR (Serpin C1/Antithrombin III antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 86067-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86067-4-RR (Serpin C1/Antithrombin III antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

Serpin C1/Antithrombin III Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 86067-4-RR

Clone No.250574G5

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

Antithrombin III, Serpin C1, SERPINC1, Antithrombin-III, AT3

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Tested Applications

• Positive WB detected in: mouse liver tissue, human plasma, human testis tissue, fetal human brain tissue, L02 cells, rat brain tissue, rat liver tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

86067-4-RR targets Serpin C1/Antithrombin III in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg3100

  Product name: recombinant human SERPINC1 protein

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 33-464 aa of NM_000488.4

  Sequence: HGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK

• Full Name: serpin peptidase inhibitor, clade C (antithrombin), member 1
• Calculated Molecular Weight: 53 kDa
• Observed Molecular Weight: 53 kDa
• GenBank Accession Number: NM_000488.4
• Gene Symbol: Serpin C1/Antithrombin III
• Gene ID (NCBI): 462
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P01008
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.