Synaptotagmin-1 Monoclonal antibody, PBS Only

Synaptotagmin-1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1


Human, Mouse, Rat, Pig, Rabbit, Chicken


WB, IHC, Indirect ELISA





Cat no : 68043-1-PBS


DKFZp781D2042, P65, SVP65, Synaptotagmin 1, synaptotagmin I, Synaptotagmin-1, SYT, SYT1, SytI

Recommended dilution

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68043-1-PBS targets Synaptotagmin-1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Pig, Rabbit, Chicken samples.

Tested Reactivity Human, Mouse, Rat, Pig, Rabbit, Chicken
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Synaptotagmin-1 fusion protein Ag6071
Full Name synaptotagmin I
Calculated Molecular Weight 48 kDa
Observed Molecular Weight60-65 kDa
GenBank Accession NumberBC058917
Gene Symbol SYT1
Gene ID (NCBI) 6857
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). SYT1 (synaptotagmin I) was firstly identified as a 65-kDa protein with a wide distribution in neuronal and neurosecretory tissue (PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse (PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth (PMID: 15492212; 11078930; 10336114).