TAB2 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 82948-5-RR (same clone as 82948-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82948-5-RR (MAP3K7IP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82948-5-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 82948-5-RR

  Biolayer interferometry (BLl) kinetic assays of 82948-5-RR against Human TAB2 were performed. The affinity constant is 65.2 pM.

TAB2 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 82948-5-PBS

Clone No.230118F1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

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Product Information

82948-5-PBS targets TAB2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag5742

  Product name: Recombinant human MAP3K7IP2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 344-693 aa of BC035910

  Sequence: SGPRTSSTSSSVNSQTLNRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQKARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDTEDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF

• Full Name: mitogen-activated protein kinase kinase kinase 7 interacting protein 2
• Calculated Molecular Weight: 76 kDa
• Observed Molecular Weight: 77 kDa
• GenBank Accession Number: BC035910
• Gene Symbol: MAP3K7IP2
• Gene ID (NCBI): 23118
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9NYJ8
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].