Product Information
85902-1-PBS targets TNFRSF13B/CD267 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with mouse samples.
Tested Reactivity | mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | TNFRSF13B/CD267 fusion protein Eg1814 Predict reactive species |
Full Name | tumor necrosis factor receptor superfamily, member 13b |
Calculated Molecular Weight | 27 kDa |
Observed Molecular Weight | 30-32 kDa |
GenBank Accession Number | NM_021349.1 |
Gene Symbol | Tnfrsf13b |
Gene ID (NCBI) | 57916 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9ET35 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.