TAF6L Recombinant monoclonal antibody, PBS Only

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• TAF6L Recombinant monoclonal antibody, PBS Only (88217-1-PBS)

TAF6L Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 88217-1-PBS

Clone No.260434E3

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

PAF65 alpha, PAF65A, PAF65-alpha, PCAF-associated factor 65-alpha, TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

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  WB analysis using 88217-1-RR (same clone as 88217-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 88217-1-RR (TAF6L antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88217-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

88217-1-PBS targets TAF6L in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag8180

  Product name: Recombinant human TAF6L protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-351 aa of BC008785

  Sequence: MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALGWKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQV

• Full Name: TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
• Calculated Molecular Weight: 622 aa, 68 kDa
• Observed Molecular Weight: 68 kDa
• GenBank Accession Number: BC008785
• Gene Symbol: TAF6L
• Gene ID (NCBI): 10629
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9Y6J9
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TAF6L (TBP-associated factor 6-like protein, also known as PAF65α) is a core component of the PCAF histone acetyltransferase complex and the STAGA transcriptional coactivation complex. This protein contains a characteristic histone folding domain (HFD) and is primarily located in the cell nucleus. As an epigenetic regulator, TAF6L works synergistically with TAF5L to promote the transcriptional elongation of RNA polymerase II by mediating H3K9ac deposition and MYC recruitment, thereby regulating embryonic stem cell pluripotency and somatic cell reprogramming.