Product Information
98527-1-PBS targets TCR Vγ5Vδ1 in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Recombinant protein Predict reactive species |
| Full Name | TCR Vγ5Vδ1 |
| Gene Symbol | |
| Gene ID (NCBI) | |
| RRID | AB_3746155 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
TCR Vγ5Vδ1 refers to a specific type of T cell receptor (TCR) found on γδ T cells. These cells are a distinct subset of T lymphocytes that play a role in immune responses, particularly in maintaining tissue integrity and responding to stress signals. The Vγ5Vδ1 TCR is uniquely expressed on a population of T cells called dendritic epidermal T cells (DETCs) that reside in the epidermis (PMID: 35260830, 35031803). The Vγ5Vδ1 TCR-CD3 complex forms an asymmetric dimer, with the Vγ5 domains of each protomer interacting to create a back-to-back structure. This dimeric form is essential for T cell activation (PMID: 38657677).
