This product is currently not available for sale.


Product Information

55307-1-AP targets TET1 in ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide Predict reactive species
Full Name tet oncogene 1
Calculated Molecular Weight 235 kDa
GenBank Accession NumberNM_030625
Gene Symbol TET1
Gene ID (NCBI) 80312
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8NFU7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TET1 ( also named CXXC6, KIAA1676 or LCX), belongs to the TET family (Tet1-3) which catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). TET1 binds throughout the genome of embryonic stem cells, with the majority of binding sites located at transcription start sites of CpG-rich promoters and within genes. Knockdown of Tet1 in preimplantation embryos resulted in a bias towards trophectoderm differentiation.Tet1 can associate with either active or repressed transcriptional states and be identified as new epigenetic factor implicated in the establishment and/or maintenance of a pluripotent epigenetic state during early embryonic development.Tet1 is highly expressed in ES cells and is rapidly downregulated upon differentiation. This antibody is specific to TET1.

Loading...