TFAM Polyclonal Antibody for ELISA
Cat no : 19998-1-AP
MtTF1, mtTFA, TCF 6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, Transcription factor 6, Transcription factor 6 like 2
Validation Data Gallery
|Sample-dependent, check data in validation data gallery|
19998-1-AP targets TFAM in ELISA applications and shows reactivity with human, mouse samples.
|Cited Species||human, mouse, rat, zebrafish|
|Host / Isotype||Rabbit / IgG|
|Full Name||transcription factor A, mitochondrial|
|Calculated molecular weight||29 kDa|
|Observed molecular weight||25 kDa|
|GenBank accession number||NM_003201|
|Gene ID (NCBI)||7019|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20oC. Aliquoting is unnecessary for -20oC storage.|
TFAM, also named as TCF6L2, MtTF1, TCF6, TCF6L1, TCF6L3 and mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. It is involved in mitochondrial transcription regulation. TFAM is required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. It activates transcription by binding immediately upstream of transcriptional start sites. TFAM is able to unwind and bend DNA. The molecular weighgt of TFAM isoforms are 25 kDa and 29 kDa，but the Ubiquitination of TFAM protein is about 35-37 kDa （PMID: 24607487）.
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