• Featured Product
  • KD/KO Validated

THOC2 Polyclonal antibody

THOC2 Polyclonal Antibody for WB, IF/ICC, IP, ELISA
Cat No. 55178-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, IP, ELISA

CXorf3, hTREX120, THO complex 2, THO complex subunit 2, Tho2

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inHEK-293T cells, HeLa cells, Jurkat cells
Positive IP detected inHeLa cells
Positive IF/ICC detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55178-1-AP targets THOC2 in WB, IF/ICC, IP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

Peptide

Predict reactive species
Full Name THO complex 2
Calculated Molecular Weight 183 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberNM_020449
Gene Symbol THOC2
Gene ID (NCBI) 57187
RRIDAB_2881283
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8NI27
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

THOC2 also termed as THO complex 2 or CXorf3 is 1593 amino acid protein, which belongs to the THOC2 family. THOC2 is a component of heteromultimeric THO/TREX (transcription/export) complex, which is a multi-protein structure consisting of THOC1, THOC2, THOC3, BAT1 and ALY. The TREX complex associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism.

Protocols

Product Specific Protocols
IF protocol for THOC2 antibody 55178-1-APDownload protocol
IP protocol for THOC2 antibody 55178-1-APDownload protocol
WB protocol for THOC2 antibody 55178-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Hum Mol Genet

Clinical and functional characterization of recurrent missense variants implicated in THOC6-related intellectual disability.

Authors - Mattioli Francesca
humanWB

Viruses

Murine Leukemia Virus Uses TREX Components for Efficient Nuclear Export of Unspliced Viral Transcripts.

Authors - Toshie Sakuma
  • KD Validated
humanWB

Mol Cell

YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks

Authors - Ning Tsao
humanWB

Int J Biol Macromol

Targeting mRNA export complex macromolecules THO subunits (Thoc2 and Thoc5) for somatic cell reprograming

Authors - Abdur Rehman

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Sonam (Verified Customer) (10-16-2025)

Worked well. highly recommend

  • Applications: Western Blot
  • Cell Tissue Type: Macrophages
Loading...
||
New chat Able
正在加载,请稍候...