TLE3 Recombinant antibody, PBS Only

TLE3 Uni-rAbTM Recombinant Antibody for IF/ICC, ELISA
Cat No. 83955-4-PBS
Clone No.240680G3

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, ELISA

GRG3, GRG 3, ESG3, ESG, Enhancer of split groucho-like protein 3

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration:  100 μg, 1 mg/ml
100 μg, 1 mg/ml

$699/ 100 μg

Freight/Packing: $40.00

Quantity

Product Information

83955-4-PBS targets TLE3 in IF/ICC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TLE3 fusion protein Ag1930 Predict reactive species
Full Name transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
Calculated Molecular Weight 772 aa, 83 kDa
GenBank Accession NumberBC015729
Gene Symbol TLE3
Gene ID (NCBI) 7090
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ04726
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

TLE3, also named as KIAA1547 and ESG3, belongs to the WD repeat Groucho/TLE family. It is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE3 is a member of the transducin-like enhancer of split (TLE) family of proteins that have been implicated in the tumorgenesis and classification of sarcomas. It is a candidate biomarker of response to taxane

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