TLR1 Polyclonal antibody

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  IHC staining of human spleen using 19816-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 19816-1-AP (TLR1 Antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human spleen using 19816-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 19816-1-AP (TLR1 Antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of human small intestine using 19816-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 19816-1-AP (TLR1 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human small intestine using 19816-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 19816-1-AP (TLR1 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human tonsillitis using 19816-1-AP

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 19816-1-AP (TLR1 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human tonsillitis using 19816-1-AP

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 19816-1-AP (TLR1 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

TLR1 Polyclonal Antibody for IHC, ELISA

Cat No. 19816-1-AP

Publications(6)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

CD281, KIAA0012, rsc786, TIL, TLR1, toll like receptor 1

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Tested Applications

• Positive IHC detected in: human spleen tissue, human small intestine tissue, human tonsillitis tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IHC: See 3 publications below

Product Information

19816-1-AP targets TLR1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag13852

  Product name: Recombinant human TLR1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 604-786 aa of BC109093

  Sequence: LDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLEKEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKLTEQAKK

• Full Name: toll-like receptor 1
• Calculated Molecular Weight: 786 aa, 90 kDa
• GenBank Accession Number: BC109093
• Gene Symbol: TLR1
• Gene ID (NCBI): 7096
• RRID: AB_2878610
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q15399
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Pharmacol Res; Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin.; Authors - Long Wang
human		Bioorg Chem; Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants; Authors - Yueyue Zhu
human	IHC	Ann Diagn Pathol; The differential expression of toll like receptors and RIG-1 correlates to the severity of infectious diseases; Authors - Madison Rice
human,mouse	IHC	Mol Neurobiol; Comparison of Neuroinflammation Induced by Hyperphosphorylated Tau Protein Versus Ab42 in Alzheimer's Disease; Authors - Madison Rice
human	IHC	Ann Diagn Pathol; The differential expression of toll like receptors and RIG-1 in the placenta of neonates with in utero infections; Authors - Madison Rice
		Infect Immun; Pmorf0222, a Virulence Factor in Pasteurella multocida, Activates Nuclear Factor Kappa B and Mitogen-Activated Protein Kinase via Toll-Like Receptor 1/2; Authors - Tenglin Xu