Product Information
19500-1-AP targets TLR1-Specific in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | toll-like receptor 1 |
| Calculated Molecular Weight | 90 kDa |
| GenBank Accession Number | NM_003263 |
| Gene Symbol | TLR1 |
| Gene ID (NCBI) | 7096 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q15399 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TLR1, also named as TIL, CD281 and KIAA0012, belongs to the Toll-like receptor family. TLR1 participates in the innate immune response to microbial agents. TlR1 cooperates with TLR2 mediates the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This antibody is specific to TLR1.
Publications
What published studies show
The TLR2 antibody (Cat# 19500-1-AP) has 1 total citation. It appears in Molecular and Cellular Endocrinology (IF 3.4), published in 2014. The associated research field is nonalcoholic steatohepatitis (NASH) in high-fat-diet-induced metabolic syndrome E3 rats, specifically investigating how down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2. The application used was Western blot (WB) in rat samples.
| Species | Application | Title |
|---|---|---|
Mol Cell Endocrinol Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats. |
