TMCO7 Polyclonal antibody

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• TMCO7 Polyclonal antibody (32692-1-AP)

• 

  WB analysis using 32692-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 32692-1-AP (TMCO7 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 32692-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 32692-1-AP (TMCO7 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

TMCO7 Polyclonal Antibody for WB, ELISA

Cat No. 32692-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

KIAA1746, TANGO6, Transmembrane and coiled-coil domain-containing protein 7, Transport and Golgi organization protein 6 homolog

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Tested Applications

• Positive WB detected in: K-562 cells, U2OS cells, SiHa cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

32692-1-AP targets TMCO7 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag38358

  Product name: Recombinant human TMCO7 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 331-665 aa of BC015617

  Sequence: MAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMVLP

• Full Name: transmembrane and coiled-coil domains 7
• Calculated Molecular Weight: 1094 aa, 120 kDa
• Observed Molecular Weight: 120 kDa
• GenBank Accession Number: BC015617
• Gene Symbol: TMCO7
• Gene ID (NCBI): 79613
• RRID: AB_3742709
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q9C0B7
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TMCO7, also known as transmembrane and coiled-coil domain 7 or TANGO6. MCO7 is predicted to play a role in protein secretion and is considered an integral component of the membrane. TMCO7 has been implicated in leukemia, with ongoing research focusing on validating its role using in vivo leukemic mouse models and protein localization studies. It is being explored as a potential therapeutic target for acute myeloid leukemia (AML).