Product Information
25506-1-AP targets TMEM74 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag22288 Product name: Recombinant human TMEM74 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-187 aa of BC030710 Sequence: MELHYLAKKSNQADLCDARDWSSRGLPGDQADTAATRAALCCQKQCASTPRATEMEGSKLSSSPASPSSSLQNSTLQPDAFPPGLLHSGNNQITAERKVCNCCSQELETSFTYVDKNINLEQRNRSSPSAKGHNHPGELGWENPNEWSQEAAISLISEEEDDTSSEATSSGKSIDYGFISAILFLVT Predict reactive species |
| Full Name | transmembrane protein 74 |
| Calculated Molecular Weight | 305 aa, 33 kDa |
| GenBank Accession Number | BC030710 |
| Gene Symbol | TMEM74 |
| Gene ID (NCBI) | 157753 |
| RRID | AB_3742149 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96NL1 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Transmembrane protein 74 (TMEM74), plays an essential role in autophagy during cell starvation and other stress conditions. TMEM74 is localized to the lysosome and autophagosome. It has been reported that TMEM74-induced autophagy may be associated with PI3K signal transduction. (PMID: 19029833, 18294959)
