TMEM98 Recombinant monoclonal antibody, PBS Only

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  IF Staining of HepG2 using 84284-4-RR (same clone as 84284-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using TMEM98 antibody (84284-4-RR, Clone: 241581G11 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84284-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84284-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84284-4-RR against Human TMEM98 were performed. The affinity constant is 0.974 nM.

TMEM98 Uni-rAb^® Recombinant Antibody for IF/ICC, Indirect ELISA

Cat No. 84284-4-PBS

Clone No.241581G11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Synonyms

241581G11, Protein TADA1, Transmembrane protein 98, UNQ536/PRO1079

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Product Information

84284-4-PBS targets TMEM98 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag6492

  Product name: Recombinant human TMEM98 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 27-226 aa of BC000526

  Sequence: CRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI

• Full Name: transmembrane protein 98
• Calculated Molecular Weight: 25 kDa
• GenBank Accession Number: BC000526
• Gene Symbol: TMEM98
• Gene ID (NCBI): 26022
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9Y2Y6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TMEM98, also named as TADA1, composed of 226 amino acid residues, is a potential single-pass transmembrane protein. It is expression in both nucleus and cytoplasm. TMEM98 was found to be over-expressed in most of the hepatocellular carcinoma tissue. MEM98 is not only a prognostic marker for patients with hepatocellular carcinoma but also a novel molecular target associated with intrinsic and acquired chemoresistance of hepatocellular carcinoma (PMID: 24608572).