|Positive WB detected in||mouse skeletal muscle tissue, human brain tissue, mouse brain tissue, mouse heart tissue|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
10145-1-AP targets TMOD1 in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||TMOD1 fusion protein Ag0192|
|Full Name||tropomodulin 1|
|Calculated molecular weight||41 kDa|
|Observed molecular weight||41 kDa|
|GenBank accession number||BC002660|
|Gene ID (NCBI)||7111|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Actin filaments control cell morphology. The length of these filaments is regulated in muscle and nonmuscle cell types by tropomodulins 1-4 (Tmod1-4), a family of proteins that cap the pointed ends of actin filaments. The molecular weight of Tmod 1 is about 40 kDa.
Transgenic Expression of the Formin Protein Fhod3 Selectively in the Embryonic Heart: Role of Actin-Binding Activity of Fhod3 and Its Sarcomeric Localization during Myofibrillogenesis.
Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart.
J Biol Chem
The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.
Am J Surg Pathol
Identification of a unique gene expression signature that differentiates hepatocellular adenoma from well-differentiated hepatocellular carcinoma.
S1P1 deletion in oligodendroglial lineage cells: Effect on differentiation and myelination.