TNFAIP8L3 Polyclonal antibody

TNFAIP8L3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 20693-1-AP

Synonyms

TIPE3, TNFAIP8 like protein 3, TNFAIP8L3

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Validation Data Gallery

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  WB analysis using 20693-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 20693-1-AP (TNFAIP8L3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: A549 cells, Jurkat cells, MCF-7 cells, mouse spleen tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

20693-1-AP targets TNFAIP8L3 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: tumor necrosis factor, alpha-induced protein 8-like 3
• Calculated Molecular Weight: 33 kDa
• Observed Molecular Weight: 37 kDa
• GenBank Accession Number: NM_207381
• Gene Symbol: TNFAIP8L3
• Gene ID (NCBI): 388121
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TNFAIP8L3 (tumor necrosis factor alpha-induced protein 8-like protein 3), also known as TIPE3, is a member of the TNFAIP8 family which also include TNFAIP8 (TIPE), TNFAIP8L1 (TIPE1) and TNFAIP8L2 (TIPE2) (PMID: 18455983; 21924498). TNFAIP8L3 is a transfer protein for phosphoinositide second messengers. It is markedly upregulated in human cancer cells and may represent a therapeutic target for treating malignant diseases (PMID: 25242044). This antibody is specific to TNFAIP8L3.

Publications

Species	Application	Title
human	WB	Hum Mol Genet; CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.; Authors - Xiaoping Huang