Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody

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  FC experiment of human PBMCs using 98100-1-RR

  1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7) and 0.25 ug Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody (98100-1-RR, Clone:241317D8) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), or Isotype Control. Cells were not fixed.

• 

  FC experiment of human PBMCs using 98100-1-RR

  1x10^6 human PBMCs were stained with 0.25 ug Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody (98100-1-RR, Clone:241317D8)(red)and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), or Isotype Control(blue). Cells were not fixed.

• 

  FC experiment of human PBMCs using 98100-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody (98100-1-RR, Clone:241317D8) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), and 0.25 ug CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7), and 0.25 ug Isotype Control. Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98100-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98100-1-RR against Human TNFRSF13B/CD267 were performed. The affinity constant is 4.18 nM.

TNFRSF13B/CD267 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98100-1-RR

Clone No.241317D8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

CD267, TNFRSF13B, TACI, CVID, 241317D8

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Tested Applications

• Positive FC detected in: human PBMCs

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98100-1-RR targets TNFRSF13B/CD267 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: tumor necrosis factor receptor superfamily, member 13B
• Calculated Molecular Weight: 293 aa, 32 kDa
• GenBank Accession Number: BC109392
• Gene Symbol: TNFRSF13B/CD267
• Gene ID (NCBI): 23495
• RRID: AB_3672247
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O14836
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.