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TNRC18 Polyclonal antibody, PBS Only

TNRC18 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 32165-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Trinucleotide repeat-containing gene 18 protein, Trinucleotide Repeat Containing 18, Long CAG trinucleotide repeat-containing gene 79 protein, KIAA1856, CAGL79

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

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Quantity

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Product Information

32165-1-PBS targets TNRC18 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag37483

Product name: Recombinant human TNRC18 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1238-1400 aa of BC131808

Sequence: PCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELER

Predict reactive species
Full Name trinucleotide repeat containing 18
Calculated Molecular Weight31 kDa
Observed Molecular Weight29 kDa
GenBank Accession NumberBC131808
Gene Symbol TNRC18
Gene ID (NCBI) 84629
RRIDAB_3670212
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity Purification
UNIPROT IDO15417
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Trinucleotide repeat containing 18 (TNRC18, also known as CAGL79 and KIAA1856) is a nucleic-acid-binding protein, which recognizes H3K9me3 to mediate the silencing of ERV class I (ERV1) elements and acts as a chromatin-associated regulator of ERVs (PMID: 27980689; 37938770). It is located in the cytosol, mitochondrion, and nucleus (PMID: 19262598). The mutation in TNRC18 may cause Fazio-Londe disease (PMID: 38188848).

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