TOM1L1 Polyclonal antibody

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• TOM1L1 Polyclonal antibody (51017-1-AP)

TOM1L1 Polyclonal Antibody for WB, ELISA

Cat No. 51017-1-AP Copied!

Publications (1)

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, ELISA

Synonyms

Src-activating and signaling molecule protein, Target of Myb-like protein 1, TOM1 L1, TOM1 like protein 1, TOM1L1 protein

• 

  WB analysis using 51017-1-AP

  BT-474 cells were subjected to SDS PAGE followed by western blot with 51017-1-AP (TOM1L1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis using 51017-1-AP

  SGC-7901 cells were subjected to SDS PAGE followed by western blot with 51017-1-AP (TOM1L1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: BT-474 cells, SGC-7901 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

51017-1-AP targets TOM1L1 in WB, IP, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag0502

  Product name: Recombinant human TOM1L1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 381-1/1 of BC029396

  Sequence:

• Full Name: target of myb1 (chicken)-like 1
• Calculated Molecular Weight: 476 aa, 53 kDa
• Observed Molecular Weight: 53 kDa
• GenBank Accession Number: BC029396
• Gene Symbol: TOM1L1
• Gene ID (NCBI): 10040
• RRID: AB_2207419
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O75674
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Target of Myb-like protein 1 (TOM1L1), also known as Srcasm, belongs to the Tom family. TOM1L1 encodes an adaptor protein characterized by an N-terminal VHS domain and a central GAT domain, which facilitates interactions with clathrin and components of the endosomal sorting machinery. Functionally, TOM1L1 serves as a substrate for Src family kinases, playing a regulatory role in growth factor signaling and membrane trafficking. It is involved in endocytosis, signal transduction, and the negative regulation of mitotic cell division. (PMID: 17977829, PMID: 26899482, PMID: 35238864, PMID: 39548458)

Publications

What published studies show

The TOM1L1 Polyclonal antibody (Cat# 51017-1-AP) has 1 total citation. It appears in Experimental Cell Research (2022), used for WB and IP in human samples. The cited study investigates mechanisms underlying melanoma invasion following MLK3 loss, placing this antibody within the research fields of cancer biology and cell signaling.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB,IP	Exp Cell Res; Mechanisms underlying melanoma invasion as a consequence of MLK3 loss; Authors - Henriette U Balinda