Product Information
20752-1-PBS targets TRAPPC5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag13185 Product name: Recombinant human TRAPPC5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-188 aa of BC042161 Sequence: MEARFTRGKSALLERALARPRTEVSLSAFALLFSELVQHCQSRVFSVAELQSRLAALGRQVGARVLDALVAREKGARRETKVLGALLFVKGAVWKALFGKEADKLEQANDDARTFYIIEREPLINTYISVPKENSTLNCASFTAGIVEAVLTHSGFPAKVTAHWHKGTTLMIKFEEAVIARDRALEGR Predict reactive species |
| Full Name | trafficking protein particle complex 5 |
| Calculated Molecular Weight | 188 aa, 21 kDa |
| Observed Molecular Weight | 21-23 kDa |
| GenBank Accession Number | BC042161 |
| Gene Symbol | TRAPPC5 |
| Gene ID (NCBI) | 126003 |
| RRID | AB_3742003 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8IUR0 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Transport protein particle (TRAPP, also known as trafficking protein particle), a multimeric guanine nucleotide-exchange factor, regulates multiple membrane trafficking pathways (PMID: 20966969). TRAPPC5 is a component of the TRAPP complexes and is involved in processes such as intracellular vesicle transport. In hepatocellular carcinoma, upregulated expression of TRAPPC5 can enhance cancer cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) and promote tumorigenesis (PMID: 35425722).
