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  • KD/KO Validated

TRIM11 Polyclonal antibody

TRIM11 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, IF, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 10851-1-AP

Synonyms

BIA1, Protein BIA1, RING finger protein 92, RNF92, TRIM11, tripartite motif containing 11



Tested Applications

Positive WB detected inHEK-293 cells, Jurkat cells, K-562 cells
Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

10851-1-AP targets TRIM11 in WB, IHC, IF, CoIP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRIM11 fusion protein Ag1308
Full Name tripartite motif-containing 11
Calculated molecular weight 52 kDa
Observed molecular weight 53 kDa
GenBank accession numberBC011629
Gene symbol TRIM11
Gene ID (NCBI) 81559
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRIM11(Tripartite motif-containing protein 11) is also named as RNF92 and Belongs to the TRIM/RBCC family. It is a member of the tripartite-motif-containing protein family and is known to destabilize humanin, an inhibitor of Alzheimer-like neuronal insults(PMID: 16904669). This protein has 3 isoforms produced by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for TRIM11 antibody 10851-1-APDownload protocol
IHC protocol for TRIM11 antibody 10851-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIHC

Hum Genome Var

Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals.

Authors - Anna B Stittrich
humanWB,IF,CoIP

Biomed Res Int

Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway.

Authors - Zhaofeng Wang
  • KD Validated
humanWB

Pathol Res Pract

miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.

Authors - Zuofei Song
humanWB,IF,CoIP

Neoplasia

TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Authors - Jianing Tang
  • KD Validated
mouseWB,IHC

FASEB J

The topological key lncRNA H2k2 from the ceRNA network promotes mesangial cell proliferation in diabetic nephropathy via the miR-449a/b/Trim11/Mek signaling pathway.

Authors - Wenyun Chen
humanIHC,IF

Oncogene

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.

Authors - Di K K