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TRIM11 Polyclonal antibody

TRIM11 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, IF, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 10851-1-AP

Synonyms

BIA1, Protein BIA1, RING finger protein 92, RNF92, TRIM11, tripartite motif containing 11



Tested Applications

Positive WB detected inHEK-293 cells, HeLa cells, Jurkat cells
Positive IHC detected inhuman colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

10851-1-AP targets TRIM11 in WB, IHC, IF, CoIP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRIM11 fusion protein Ag1308
Full Name tripartite motif-containing 11
Calculated molecular weight 52 kDa
Observed molecular weight 53 kDa
GenBank accession numberBC011629
Gene symbol TRIM11
Gene ID (NCBI) 81559
RRIDAB_2209210
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TRIM11(Tripartite motif-containing protein 11) is also named as RNF92 and Belongs to the TRIM/RBCC family. It is a member of the tripartite-motif-containing protein family and is known to destabilize humanin, an inhibitor of Alzheimer-like neuronal insults(PMID: 16904669). This protein has 3 isoforms produced by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for TRIM11 antibody 10851-1-APDownload protocol
IHC protocol for TRIM11 antibody 10851-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

Science

TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease

Authors - Zi-Yang Zhang
mouseWB,IF,CoIP

J Hazard Mater

The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM2.5 exposure-induced pulmonary fibrosis of mice.

Authors - Yaling Zhang
humanIHC,IF

Oncogene

TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.

Authors - Di K K
mouseWB,IHC

FASEB J

The topological key lncRNA H2k2 from the ceRNA network promotes mesangial cell proliferation in diabetic nephropathy via the miR-449a/b/Trim11/Mek signaling pathway.

Authors - Wenyun Chen
humanIF,CoIP, WB

Int J Biol Sci

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.

Authors - Jianing Tang
humanWB,IF,CoIP

Neoplasia

TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Authors - Jianing Tang
  • KD Validated